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J.Pharma · Anti-Aging · Research Peptide

MT-2 Melanotan 2

A synthetic alpha-MSH analog studied for its activity at melanocortin receptors — research spans melanogenesis, appetite regulation, and body composition.

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Anti-Aging · Research Compound

About MT-2 (Melanotan 2)

Melanotan 2 (MT-2) is a synthetic cyclic heptapeptide and analog of alpha-melanocyte-stimulating hormone (alpha-MSH), a naturally occurring hormone involved in pigmentation and a range of other physiological processes. MT-2 was originally developed in research exploring sunless tanning, and remains widely studied for its activity at the melanocortin receptor family.

MT-2 acts as a non-selective melanocortin receptor agonist. Activation of MC1R on melanocytes stimulates melanogenesis, shifting pigment production toward eumelanin (the darker pigment) and away from pheomelanin. Activation of MC3R and MC4R, expressed in the central nervous system, has been implicated in research on appetite regulation, libido, and body composition. This same melanocortin receptor research line is the precursor to PT-141 (bremelanotide), a more MC4R-selective compound studied specifically for sexual arousal research.

Purity
≥99%
HPLC-UV verified
Identity
LC-MS Confirmed
Mass spectrometry
Form
Lyophilized Powder
Requires reconstitution
Storage
Lyophilized: Room temp or 2–8°C, light-protected
After reconstitution: 2–8°C, foil-wrapped
Available Sizes
10mg
Lyophilized powder · 99%+ purity
$30
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🧪 Reconstitution & Storage
Reconstitute the 10mg vial with 1–2 mL Bacteriostatic Water for a concentration of approximately 5–10 mg/mL. Inject the BAC Water slowly down the vial wall and swirl gently — do not shake. MT-2 is light-sensitive: keep the lyophilized vial in its original packaging away from direct light, and store the reconstituted solution refrigerated at 2–8°C, wrapped in foil or kept in a dark container. Visit our full Reconstitution Guide and Dosing Calculator for detailed instructions.
Research Context

Research Applications

MT-2 is used in research investigating melanocortin receptor pharmacology, melanogenesis and pigmentation pathways, appetite regulation, and body composition. It is also frequently referenced in research literature as a precursor to more receptor-selective melanocortin agonists, including MC4R-targeted compounds.

For research use only. All products sold by J.Pharma are intended strictly for in vitro laboratory research. Not for human or veterinary use. Not FDA approved for any therapeutic purpose.
FAQ

Common Questions

What is Melanotan 2?
Melanotan 2 (MT-2) is a synthetic cyclic heptapeptide and analog of alpha-melanocyte-stimulating hormone (alpha-MSH). It was originally developed as part of research into sunless tanning agents and has since been studied for a broader range of melanocortin-receptor-related effects.
What is the mechanism of action?
MT-2 acts as a non-selective agonist at melanocortin receptors. Activation of MC1R on melanocytes stimulates melanogenesis — the production of eumelanin, the darker skin pigment. Activation of MC3R and MC4R, found in the central nervous system, has been implicated in research on appetite regulation, libido, and body composition. This receptor family is also the basis of the research line that led to PT-141 (bremelanotide).
Why is Melanotan 2 light-sensitive?
Like many peptides, MT-2 can degrade when exposed to prolonged light, particularly UV light. Protecting both the lyophilized powder and the reconstituted solution from light helps preserve the peptide's structural integrity and stability over its storage life.
How do I reconstitute and store MT-2?
Reconstitute the 10mg vial with 1–2 mL Bacteriostatic Water for a concentration of approximately 5–10 mg/mL. Inject the BAC Water slowly down the vial wall and swirl gently — do not shake. Store the reconstituted solution refrigerated at 2–8°C, wrapped in foil or kept in a dark container to protect it from light.
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Regulatory Notice

None of the statements on this website have been reviewed or approved by the U.S. Food and Drug Administration. J.Pharma products are not intended to diagnose, treat, cure, or prevent any disease or medical condition. All products are sold strictly for in vitro laboratory research purposes. They are not for human or animal use of any kind. DiPerna Services, LLC d/b/a J.Pharma is not a compounding pharmacy or outsourcing facility as defined under Sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act.